Nanoparticles in Bioimaging

Facile Synthesis and Potential Bioimaging Applications of Hybrid Upconverting and Plasmonic NaGdF4: Yb3+, Er3+/Silica/Gold Nanoparticles

We present a simple method for preparing water dispersible NaGdF4: Yb3+, Er3+/silica/gold nanoparticles. The emission intensity and color of the upconverting cores are modulated by the plasmonic absorbance and field enhancement from the gold nanoparticles. The applicability of hybrid NPs for multi-modal bioimaging probes is illustrated by in vitro confocal microscopy of living cancer cells.

Two-Photon Chromophore-Polymer Conjugates Grafted onto Gold Nanoparticles as Fluorescent Probes for Bioimaging and Photodynamic Therapy Applications

Strategies for Preparing Albumin-based Nanoparticles for Multifunctional Bioimaging and Drug Delivery

Biosafety is the primary concern in clinical translation of nanomedicine. As an intrinsic ingredient of human blood without immunogenicity and encouraged by its successful clinical application in Abraxane, albumin has been regarded as a promising material to produce nanoparticles for bioimaging and drug delivery. The strategies for synthesizing albumin-based nanoparticles could be generally cat...

Microstructural Characterization of Silver Nanoparticles for Bioimaging Applications

Silver nanoparticles are emerging as a powerful tool in bioimaging applications owing to their unique plasmonic properties i.e., extremely high molar extinction coefficients, resonant Rayleigh scattering and enhanced local electromagnetic fields [1]. Through the optimization of these properties, by controlling composition, size, shape, and interparticle spacing of nanoparticles and their assemb...

Fluorogen-free aggregation induced NIR emission from gold nanoparticles.

Controlled diluted aqua regia addition leads to NIR (near infrared) luminescence from aggregated gold nanoparticles at 916 nm. This turn-on luminescence has been observed for gold nanoparticles, regardless of reductants used in their preparation. These aggregated nanoparticles are nontoxic and have been used for bioimaging in human liver carcinoma cells.